Scientists have developed a method that makes it possible to quickly identify so-called obstructive strokes, the development of which leads to the formation of blood clots in the large arteries of the patient's brain.
American molecular biologists have discovered that serious forms of stroke can be quickly detected with a 93% probability by the presence of two protein biomarkers in patients' blood: the molecules GFAP and D. This was announced by the press service of the American Brigham Hospital.
Joshua Bernstock, a researcher at Brigham Hospital, said: “If a blood clot occurs in the large arteries of the brain, it can be quickly removed and normal blood flow restored by “mechanical thrombectomy,” and the faster this treatment is applied, the greater the patient’s chances of remaining healthy. "The method we have obtained will accelerate the receipt of such treatment for a large number of patients throughout the Earth."
Scientists have developed a method that makes it possible to quickly and cheaply identify embolic strokes that form during the development of blood clots in the large arteries of the patient's brain. It is dangerous for patients' lives, because during its growth, brain cells begin to die in the first minutes after blood flow stops.
Usually, patients' lives can be saved if this clot is identified immediately after the patient is admitted to hospital and surgically removed as part of a "mechanical thrombectomy" procedure. So far, there are no cheap methods that allow doctors to identify such a blood clot without using CT scanning, in addition to other expensive procedures.
American molecular biologists recently discovered that the development of obstructive strokes is accompanied by an increase in the concentration of two proteins, GFAP peptide and D-dimer, in blood samples taken from capillaries. This makes it possible to quickly identify blood clots within large arteries using relatively simple blood tests with the FAST-ED test, which aims to identify characteristic stroke-related disturbances in the functioning of the human body.
Scientists tested this method on 323 patients who were transferred to Florida hospitals with strokes of varying severity. These studies showed that the methods developed by biologists make it possible to detect obstructive strokes with a probability of 93% and take optimal measures in the first six hours after the onset of symptoms. Scientists concluded that this approach would increase hope for the patient's chances of survival.
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