India has been successful in making medicines for four rare diseases in just one year. There is a plan to deliver these medicines to Jan Aushadhi Kendra also.
New Delhi : India has made medicines for four rare diseases. Earlier its price was in crores, but now this medicine will be available for just a few lakhs. Apart from this, syrup for sickle cell disease is also being made. A year ago, India had started work on making medicines for 13 types of rare diseases, out of which it has been successful in making medicines for four diseases.
With this success of India, medicines worth crores of rupees will now be available in the country for just a few lakh rupees. There are about 8.4 crore to 10 crore rare disease patients in India. 80% of rare diseases are genetic, which affect children since childhood.
India has been successful in making medicines for four rare diseases in just one year. There is a plan to deliver these medicines to Jan Aushadhi Kendra also.
India made medicines for these four rare diseases:-
Tyrosenemia Type 1: Annual expenditure earlier was around Rs 3.5 crore, now around Rs 2.5 lakh
Gaucher: Earlier it cost Rs 2.5 crores to Rs 6.5 crores, now the price is Rs 2.5 lakhs.
Wilson: Used to cost Rs 1.8 to Rs 3.6 crore annually, now the cost is Rs 3.5 lakh
Dravet: Price around Rs 6 to 20 lakh annually, now Rs 1 to 5 lakh
The medicines that have been made for these four diseases are: -
Nitisinone,
Eliglusat (3 Crore to 2.5 Lakh)
Trientine (from 2.2 crores to now 2.2 lakhs)
Cannabidiol (from 7 to 34 lakh now 1 to 5 lakh)
Work on making medicines for these diseases continues: -
Phenylketonuria
Hyperammonemia
Cytic Fibrosis
sickle cell
Four more medicines are coming in a few months.
Sickle Cell Anemia: This is a genetic disease, in childhood, children have difficulty in taking tablets till the age of 5 years, hence work is being done on the syrup.
Its tablet is available and now the company has also prepared the syrup and submitted it for approval. Now it will be possible to buy syrup for Rs 400 instead of Rs 70 thousand because of 'Made in India'.
CSIR is doing research on this sickle cell anemia. Work is underway to correct the gene.
GPS signal of planes suddenly disappears in the sky of Middle East, DGCA alerts airlines
In late September, several commercial flights near Iran were grounded after their navigation systems were jammed. One of these flights became a victim of spoofing and flew into Iranian airspace almost without permission.
DGCA's primary area of concern is a busy airspace over northern Iraq and Azerbaijan.
special things
DGCA had formed an internal committee on 4 October 2023.
12 different incidents of spoofing till September this year
No culprit has been identified yet
New Delhi:In the last few days, several cases of jamming and spoofing of the Global Navigation Satellite System (GNSS) have been reported in the airspace of the Middle East. Concerned by these reports, the Civil Aviation Regulator (DGCA) has issued a circular for all Indian airlines. The purpose of the DGCA circular is to alert airlines about the nature of the threat and how to respond to it.
"The aviation industry is grappling with uncertainties due to new threats and reports of GNSS (Global Navigation Satellite System) jamming and spoofing," the DGCA circular said.
A senior DGCA official said that the circular was issued after forming an internal committee on October 4 in the wake of increasing reports of interference by the Global Navigation Satellite System in the Middle East airspace. In this circular, emphasis has been laid on reducing security related threats. Especially during flight, efforts have been made to protect the Global Navigation Satellite System from jamming and to deal with spoofing threats.
In late September, several commercial flights near Iran were grounded after their navigation systems were jammed. One of these flights became a victim of spoofing and flew into Iranian airspace almost without permission.
According to OpsGroup, a group of professional pilots, flight dispatchers, schedulers and controllers have raised this issue with the DGCA.
How does spoofing work?
Aircraft flying in some parts of the Middle East initially receive fake GPS signals. The purpose of this signal is to give wrong message to the in-build system in the aircraft. The signal is often so strong that the aircraft's system begins to interpret it as correct. The result is that the Inertial Reference System (IRS) becomes unstable within a few minutes. In many cases the aircraft loses all its navigation capabilities.
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In which areas did such incidents occur?
DGCA's primary area of concern is a busy airspace over northern Iraq and Azerbaijan. Many such incidents have happened near Erbil. 12 separate incidents were recorded till September this year, the latest of which was recorded on November 20 in Turkey near Ankara.
Who is responsible for this?
However, no culprit has been identified yet. It is believed that jamming and spoofing is taking place due to the deployment of military electronic warfare systems in areas where there is regional tension.
What is in the DGCA circular?
A DGCA official said, “The circular is based on the recommendations of the committee to deal with the emerging threat considering best practices, latest developments and ICAO guidance on the matter. This circular has asked all aircraft operators, pilots, air navigation service provider (ANSP) companies along with air traffic controllers to remain alert to deal with any challenge. In this, after assessing the emergency, it has been advised to bring that danger to the minimum level.
“It also provides a mechanism for the ANSP to set up a threat surveillance and analysis network with problem-solving as well as reactive threat monitoring, data,” the official said.